Human herpesvirus 6 positive Reed-Sternberg cells in nodular sclerosis Hodgkin lymphoma
نویسندگان
چکیده
منابع مشابه
Nodular sclerosis Hodgkin lymphoma with classic Reed-Sternberg cells.
A 15-year-old young man presented to the emergency department with a 3-week history of sharp left-sided chest pain, shortness of breath on exertion, and a low-grade intermittent fever. Chest radiograph revealed increased density in the upper left lobe, thus he was treated with antibiotics for query pneumonia. Although his fever subsided, the patient continued to have chest pain, and subsequentl...
متن کاملCD20 Over-Expression in Hodgkin-Reed-Sternberg Cells of Classical Hodgkin Lymphoma: the Neglected Quest
We have scrutinized a previously analyzed cohort of classical Hodgkin lymphoma patients for evidence of a CD20 over-expression. This was pursued in order to determine whether all the 24 (12.6%) CD20+++ patients had clinical and/or biological profiles which would warrant a separate consideration and treatment or would carry a different outcome from our 166 CD20 (-) classical Hodgkin lymphoma pat...
متن کاملSignal transducer and activator of transcription 6 is frequently activated in Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma.
The unique clinicopathologic features of Hodgkin lymphoma (HL) are due to the multiple cytokines produced by its neoplastic cells, the Hodgkin and Reed-Sternberg (HRS) cells. Cytokine signaling is mediated through the signal transducer and activator of transcription (STAT) family of transcription factors. Immunoblotting and immunohistochemistry were used to examine cell lines and tissue section...
متن کاملReed-Sternberg-like cells in follicular lymphoma
which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 32-year-old woman presented with abdominal bloating and postprandial discomfort for 3 weeks. Multiple neck and axillary lymph nodes were palpable on physical examination. The lymph nodes were involved by low grade follicular lymphoma with effacement by clo...
متن کامل[Prognostic significance of CD20 expression in Hodgkin and Reed-Sternberg cells of classical Hodgkin's Lymphoma].
BACKGROUND & OBJECTIVE Hodgkin and Reed-Sternberg (HRS) cells of classical Hodgkin's Lymphoma (CHL) express B-cell marker CD20 with a reported frequency of 5%-58%. The prognostic significance of CD20 expression in HRS cells of CHL is still controversial. This study was to investigate the prognostic significance of CD20 expression in naive CHL patients. METHODS The expression of CD20, CD15 and...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2012
ISSN: 0007-1048
DOI: 10.1111/j.1365-2141.2012.09206.x